Can the .hdf files generated by AlphaTims be supported by AlphaDIA?

[JianSong2018]

Hi, I found that AlphaDIA does not support the .hdf from AlphaTims. If that’s the case, then what’s the point of generating the HDF files?

Best,
Jian

[mschwoer]

Hi,
true, this is currently not supported. The .hdf files can only be read with alphatims, not alphadia. What is your usecase?

best,
Magnus

[JianSong2018]

We have internal 4D data and would like to convert it into a format that can also be identified by AlphaDIA. However, converting 4D data to mzML results in prohibitively large file sizes. If HDF cannot be utilized by any database search engine, its practical value would be greatly diminished.

Best,
Jian

[mschwoer]

Hi,

we have been discussing this internally and will reprioritize it based on your feedback.
I'll come back to you in ~4 weeks.

best,
Magnus